2020-12-09 Artykuł

Wpływ suplementacji hormonu wzrostu (GH) na wybrane czynniki modulujące ryzyko sercowo-naczyniowe

Ważnym aspektem działania hormonu wzrostu (GH) jest jego wpływ na układ sercowo-naczyniowy. Wyniki licznych badań wskazują na korzystne działanie suplementacji tego hormonu na poziom ryzyka sercowo-naczyniowego. Działanie GH na poszczególne składowe ryzyka sercowo-naczyniowego jest zróżnicowane i zależy od wielu czynników, m.in. od wieku i płci. Hormon wzrostu w układzie krążenia wywiera pozytywny, jak i negatywny wpływ.

Do pozytywnych skutków suplementacji GH można zaliczyć poprawę profilu lipidowego oraz zwiększenie masy mięśnia sercowego u chorych z niewydolnością serca. Do niekorzystnych skutków suplementacji GH zalicza się nadciśnienie oraz wzrost insulinooporności. Jednak rzadko powikłaniem suplementacji hormonu wzrostu jest cukrzyca. GH powoduje również wzrost krzepliwości krwi. Opierając się na aktualnej literaturze, nie można jednoznacznie stwierdzić, że suplementacja GH powoduje spadek ryzyka sercowo-naczyniowego. Jednak dostępne wyniki badań wskazują na prawdziwość tej hipotezy.

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Autor: Mikołaj Czerwiński , lek. Paweł Szandrowski, dr hab. n. med., prof. UMK Michał Wiciński

Data publikacji: 2020-12-09

Źródło: "Lek w Polsce" nr 10/11/2020

Słowa kluczowe: hormon wzrostu, GH, układ krążenia, ryzyko sercowo-naczyniowe

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